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Specifically, the allosteric binding throughout the limbic procedure leads to the anxiolytic effects seen with diazepam. Allosteric binding within the spinal wire and motor neurons is the principal mediator of your myorelaxant effects found with diazepam.
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Distribution: Diazepam is highly lipophilic. Although You will find a reasonably swift onset of action, the drug promptly redistributes. Diazepam and its metabolites have higher plasma protein binding.
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Zavisnost obično počinje tako što pacijent dobije Bensedin na recept, a onda samoinicijativno uvećava doze ili skraćuje vreme između dva uzimanja da bi dejstvo Bensedina bilo intenzivnije. Organizam se navikava na njegovo prisustvo i postaje tolerantan na Bensedin lek.